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https://www2.illinois.gov/business/manage-your-business/IDPH/end-stage-renal
End Stage Renal Dialysis Facility Medicare Certification
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IDPH certifies End Stage Renal Dialysis facilities that provide dialysis treatment or dialysis training to individuals with end stage renal disease to be eligible for Medicare reimbursement.
https://www2.illinois.gov/business/manage-your-business/IEPA/lab-accreditation
IEPA Lab Accreditation Rules
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Rules and Regulations for Lab Accreditation
https://www2.illinois.gov/business/manage-your-business/DNR/ginseng-grower
Ginseng Dealer/Grower License
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Ginseng licenses can be purchased online through the DNR DIRECT license/permit system
https://www2.illinois.gov/business/manage-your-business/IDOT/utility-permits
Utility Permits
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Provides the process and resources for applying for a permit for Utility Work in right-of-way (new installations, maintenance of existing utilities and utility relocations; mainly for municipalities and utility companies.)
https://www2.illinois.gov/business/manage-your-business/IDPH/non-community-water
Non-Community Public Water System Construction Application
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Non-community public water systems are facilities, such as schools, factories, restaurants, resorts, and churches, served by their own water supply (usually a well). These facilities are required to provide a safe and adequate supply of water under the federal Safe Drinking Water Act (SDWA). Currently, there are nearly 3,800 non-community public water systems in Illinois. IDPH is responsible for assuring the compliance of non-community water systems with the SDWA.
https://www2.illinois.gov/business/manage-your-business/IDOT/metals-material-approval
Metals Material Approval
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Contractual metals and miscellaneous materials used in the State’s highway construction and maintenance programs are required by both the Federal Highway Administration and the State of Illinois Departmental Policy. In addition to materials testing the Department has several certification/qualification/approval programs requiring field inspection either at the manufacturing location or the job site.
https://www2.illinois.gov/business/manage-your-business/IDOT/soils-material-approval
Soils Material Approval
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Provides process and how to get soil materials approved.
https://www2.illinois.gov/business/manage-your-business/IDOT/advertising-permits
Outdoor Advertising Permits
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This section outlines the process by which to legally Advertise Adjacent to Primary and Interstate Highways.
https://www2.illinois.gov/business/manage-your-business/ICC/motor-carrier
Register Motor Carrier
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Information on Public Carrier Certificate and Certificate of Exemption
https://www2.illinois.gov/business/manage-your-business/IDOT/highway-agreements
Highway Authority Agreements
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An agreement with a highway authority may be used where a property owner has contaminated public right-of-way or where the public right-of-way may become impacted in the future.
https://www2.illinois.gov/business/manage-your-business/IDPH/Certificate of Free Sale - Public Health
Certificate of Free Sale - Public Health
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IDPH issues Certificates of Free Sale to Illinois Food and Dairy Manufacturers, Processors, Warehousers and Packers and other facilities which the Division of Food, Drugs and Dairies inspects, permits or surveys. 
https://www2.illinois.gov/business/manage-your-business/IDOT/engineering-procurements
Engineering/Architectural Procurements
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Prior to any road or bridge being constructed, the department identifies the need for specialized work. In order to work for the department in this capacity, firms must first seek prequalification in specialized categories. Once prequalified a firm is eligible to submit a statement of interest on advertised projects.
https://www2.illinois.gov/business/manage-your-business/IDOT/doing-business-idot
Doing Business with Illinois Dept. Transportation
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IDOT continually advertises its need for professional services, construction and specialized material needs through its "Doing Business with IDOT" site.
https://www2.illinois.gov/business/manage-your-business/IEPA/drinking-water-operator
Drinking Water Operator Certification
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To protect public health, drinking water treatment systems must be properly operated and maintained. For this reason, and to protect the financial investment of drinking water supplies, the Illinois EPA operates a Drinking Water Operator Certification Program that certifies the technical competency of operators of community water supplies.
https://www2.illinois.gov/business/manage-your-business/GOV/business-rules-regulations
Lookup Business Rules & Regulations
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Links to laws and how they're enforced related to doing business in Illinois
https://www2.illinois.gov/business/manage-your-business/IDOR/business-tax-account
Business Tax Account Summary
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View e-Services available for businesses.
https://www2.illinois.gov/business/manage-your-business/IDOT/disadvantaged-business-certification
Disadvantaged Business Enterprise Certification
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Pursuant to the requirements of federal regulations, all federal-aid recipients implement a “one-stop” certification process for Disadvantaged Business Enterprises (DBEs). Businesses involved in highway construction-related services (non-vertical), consultant, and supplier/equipment, rental/trucking services are considered for participation in IDOT’s DBE Program.
https://www2.illinois.gov/business/manage-your-business/DNR/timber-buyer
Timber Buyer Information
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Timber Buyer information is available from the IDNR Office of Forest Resources.
https://www2.illinois.gov/business/manage-your-business/DCEO/business-tax-incentives
Find State Business Tax Incentives Programs
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Illinois offers a competitive range of incentives for locating and expanding your business
https://www2.illinois.gov/business/manage-your-business/IDOR/business-taxes-pay
Business Taxes Web Pay
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Make business tax payments online with MyTax Illinois.
https://www2.illinois.gov/business/manage-your-business/IDOT/special-sign-permits
Special Sign Permits
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Provides information on special sign programs that provide motorists with business identification and directional information for eligible motorist services, attractions, and tourist-oriented businesses.
https://www2.illinois.gov/business/manage-your-business/IDOT/map-weigh-stations
Map of Illinois Weigh Stations
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IDOT Map of Weigh Stations
https://www2.illinois.gov/business/manage-your-business/CMS/become-vendor
Become a Vendor & sell to state government
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Learn how to do business with the state and sell products and services as a vendor
https://www2.illinois.gov/business/manage-your-business/IDOR/certificate-resale
Certificate of Resale
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Learn more about Certificate of Resale requirements for Illinois businesses.