Bupropion |
|
Morphologic- limited evidence of cardiac malformations; increased risk for pulmonary hypertension
Behavioral- limited evidence of increased risk of ADHD |
|
2.0% |
Seizures |
Citalopram |
|
Morphologic- risk of neural tube defect
Behavioral- none found |
|
0.7% - 9.0% |
Uneasy sleep, drowsiness, irritability, weight loss |
Desipramine |
|
Morphologic- none found
Behavioral- none found |
Maternal side effects additive to pregnancy effects (sedation, constipation, tachycardia)
Orthostatic hypotension, risking decreased placental perfusion
Fetal and neonatal side effects: tachycardia, urinary retention
|
1.0% |
Agitation of newborn, potential triggering of seizure activity if there is a history of seizures |
Duloxetine |
|
Morphologic- unknown
Behavioral- unknown |
|
0.1% |
Unknown |
Escitalopram |
|
Morphologic- unknown
Behavioral- unknown |
|
3.9% - 7.9% |
Enterocolitis |
Fluoxetine |
|
Morphologic- increased risk of cardiovascular malformations*
Behavioral- none found |
|
1.2% - 12.0% |
Excessive crying,
irritability, vomiting, watery stools, difficulty sleeping, tremor, somnolence, hypotonia, decreased weight gain, hyperglycemia |
Mirtazapine |
Fewer sexual side effects
Helps restore appetite in women who are not gaining weight
Less likely to exacerbate nausea and vomiting
|
Morphologic- none found
Behavioral- unknown |
|
0.6% - 2.8% |
None |
Nortriptyline |
|
Morphologic- none found
Behavioral- none found |
Maternal side effects additive to pregnancy effects (sedation, constipation, tachycardia)
Orthostatic hypotension, risking decreased placental perfusion
Fetal and neonatal side effects: tachycardia, urinary retention
|
1.3% |
None |
Paroxetine |
|
Morphologic- possible increased risk of cardiovascular malformations
Behavioral- unknown |
|
0.1% - 4.3% |
Irritability, sleepiness, constipation, SIADH |
Sertraline |
|
Morphologic- unlikely increased risk of omphalocele and septal defects*
Behavioral- none found |
|
0.4% - 2.3% |
Drug of choice by OBs & Pediatricians |
Venlafaxine |
|
Morphologic- none found
Behavioral- unknown |
|
5.2% - 7.6% |
Decreased weight gain |
Desvenlafaxine |
|
Morphologic- unknown
Behavioral- unknown |
|
Unknown |
Unknown |
---|